Keith Loeb, MD, PhD

Professor

Keith Loeb, MD, PhD

Pronouns:

He, him

E-mail:

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Office Location:

SCCA - Room - G7-910

Mailing Address:

Box 358080
825 Eastlake Ave E
Seattle, WA 98109


Clinical and Research Background

I am interested in how abnormal cell cycle regulation impacts cell proliferation differentiation and stem cell maintenance focusing on myeloid disorders including myelodysplastic syndrome, myeloproliferative neoplasm and acute myeloid leukemia. Our current focus is on erythroid maturation using a function shRNA study to challenge cell cycle exit during erythropoiesis. We are also studying erythroleukemia arising from a Sleeping Beauty transposon mediated insertional mutagenesis in mice expressing a stabilized form of cyclin E.

My clinical service specializes in bone marrow transplant Pathology including accessing hematologic malignancy, graft-vs-host disease and infection in stem cell transplant patients.

Board Certifications

Hematopathology, Anatomic and Clinical Pathology

Academic and Medical Appointments

Professor, Translational Science and Therapeutics Division, Fred Hutch Cancer, Seattle, WA, 2024-present

Professor, Public Health Science Division, Fred Hutch Cancer Center, Seattle, WA, 2024-present

Professor, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 2024-present

Associate Member, Divisions of Clinical Research and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 2014-present

Associate Professor, Department of Pathology, University of Washington Medical Center, Seattle, WA, 2014-2024

Adjunct Associate Professor, Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA, 2014-2024

Assistant Professor, Department of Pathology, University of Washington Medical Center, Seattle, WA, 2007-2014

Adjunct Assistant Professor, Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA, 2008-2014

Education and Training

Hematopathology Fellowship, University of Washington Medical Center, Seattle, WA.

Senior Postdoctoral Fellowship with Jim Roberts, Fred Hutchinson Cancer Research Center, Seattle, WA.

Pathology Residency Training (Combined AP/CP), University of Washington Medical Center, Seattle, WA.

Medical College of Wisconsin, Milwaukee, WI, M.D.

Medical College of Wisconsin, Milwaukee, WI, Biochemistry, Ph.D.

Wesleyan University, Middletown, CT, Biology, B.A.

Publications

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