Danny E. Miller, MD, PhD

Clinical and Research Background

​Dr. Miller’s laboratory uses long-read DNA and RNA sequencing to identify missing disease-causing genetic changes difficult to detect using standard genetic testing. These include complex changes difficult to detect or resolve with short-read sequencing, and variants in regions of the genome that were previously inaccessible to prior technologies. His group is interested in developing long-read sequencing-based clinical tests to simplify clinical genetic testing, increase the diagnostic rate, and shorten the time required to arrive at a genetic diagnosis. Clinically, he is an attending physician in the Department of Pediatrics, Division of Genetic medicine and sees patients in both general genetics and skeletal dysplasia clinics at Seattle Children’s Hospital.