ThyroSeq® Genomic Classifier (Sendout)

General Information

Lab Name

Lab Code

1095

Description

ThyroSeq® Genomic Classifier (GC) is used for the pre-operative assessment of thyroid nodules with indeterminate cytology using DNA and RNA sequencing by NGS, and offers an assessment of cancer probability in a given nodule and additionally provides information on cancer prognosis.

Thyroseq vials are submitted with Cytopathology FNA orders (NONGYN in EPIC). HMC Cytology will send out the vial for testing if FNA results are indeterminate (Bethesda III: Atypia of Undetermined Signifance or Bethesda IV: Suspicious for Follicular Neoplasm).

Synonyms

CBLPath, FNA, Molecular Thyroid, Thyroid Genomic Classifier

Interpretation

Method

Next-generation sequencing

Reference Range

Ordering & Collection

Specimen Type

FNA pass collected in ThyroSeq vial

Collection

FNA Collection Instructions For Clinicians:

  1. Label Thyroseq vial with Patient's name and specimen site using labels from the test requisition form.
  2. Place a full SECOND FNA pass into the ThyroseqPreserve solution vial
  3. After collection, secure the tube cap and invert several times to mix the collected sample. Place into dark bag. Package Thyroseq vial and Cytology FNA sample together and deliver to the Lab immediately.
  4. HMC Cytology will send out the Throseq vial for testing if the Cytology FNA results are indeterminate (Bethesda III: Atypia of Undetermined Signifance or Bethesda IV: Suspicious for Follicular Neoplasm)

Instructions for storage of ThyroSeq vials AFTER specimen collection:

  • No longer than 3 hours at room temp (15-25ºC)
  • No longer than 24 hrs refrigerated (2-8ºC)
  • Up to 12 months in freezer (-15 to -25ºC)

Thyroseq vials may be obtained by contacting Cytology, 206-744-0355.

Handling Instructions

All samples must be routed through the HMC Cytology department for send out to CBLPath.

Processing

All inquiries must route through Cytology.

SPS handling instructions:

Refrigerate upon receipt and forward to Cytology. Sample unacceptable if left at room temperature greater than 3 hours.

Performance

LIS Dept Code

Performing Location(s)

Sendout CBLPath
877-225-7284

760 Westchester Avenue
Rye Brook, NY 10573

Cytology Sendout. Contact 206-744-0355 for inquiries.

Frequency

Reported: 7-10 business days from sample receipt at CBL Path Laboratories

Available STAT?

No

Billing & Coding

CPT codes

LOINC