Anaplasma phagocytophilum Antibody, IgG (Sendout)
General Information
Lab Name
Lab Code
216
External Test Id
ANAP
Description
Useful For:
- As an adjunct in the diagnosis of human granulocytic ehrlichiosis
- Seroepidemiological surveys of the prevalence of the infection in certain populations
Testing Algorithm:
Synonyms
ANAP, Anaplasma phagocytophilum, Ehrlichiosis, HGA, HGE, Human Granulocytic Anaplasmosis, Human Granulocytic Ehrlichiosis
Interpretation
Method
Immunofluorescence Assay (IFA)
Ref. Range Notes
Reference Values: <1:64
Interpretation:
A positive result of an immunofluorescence assay (IFA) test (titer > or =1:64) suggests current or previous infection with human granulocytic ehrlichiosis. In general, the higher the titer, the more likely it is that the patient has an active infection.
Seroconversion may also be demonstrated by a significant increase in IFA titers.
Interferences and Limitations
Cautions:
Previous episodes of human granulocytic ehrlichiosis may produce a positive serologic result.
In rare instances, clinical evidence of infection may also be derived by direct microscopic examination of Giemsa- or Diff-Quik-stained peripheral blood buffy coat smears, which may reveal clusters of round, dark-purple stained, small dots, or clusters of dots (morulae) in the cytoplasm of polymorphonuclear cells. However, this is a very insensitive method.
Performance characteristics have not been established for hemolyzed or lipemic specimens.
Guidelines
Ordering & Collection
Specimen Type
Collection
Collect 3 mL blood in RED TOP tube or GOLD SST
Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Stability: Refrigerated (preferred): 14 days; Frozen: 14 days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, or heat-inactivated specimen.
Quantity
requested: 0.5 mL serum
minimum: 0.4 mL serum
Processing
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Login: SPMSND-;REFRIG
- MSNDTO: MAYOSD
- MSPTYP: SERUM
- MTSTRQ: ;Anaplasma phagocytophilum IgG (Mayo Test ANAP)
Sendouts:
- Order Mayo Test: ANAP.
Stability: Refrigerated (preferred): 14 days; Frozen: 14 days; Ambient: Unacceptable.
Reject Due To: Gross hemolysis, gross lipemia, gross icterus, or heat-inactivated specimen.
Performance
LIS Dept Code
Performing Location(s)
Sendout |
Mayo Clinic Laboratories (Superior Drive)
800-533-1710 3050 Superior Drive NW |
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Frequency
Performed: Monday - Friday. Report Available: 1-3 days.
Available STAT?
No
Billing & Coding
CPT codes
Billing Comments
CPT: 86666
LOINC