Laboratory Test Guide

Euglobulin Clot Lysis Time

General Information

Lab Name

Lab Code

667

External Test Id

FEUCT

Description

Clinical Information: Euglobulin clot lysis time (ECLT) provides an overall assessment of the fibrinolysis system by measuring the time for an in vitro clot to dissolve in the absence of the normal plasmin inhibitors. ECLT is used to assess the fibrinolytic system and to monitor patients on urokinase or streptokinase fibrinolytic therapy. More modern alternatives to this assay are the Thromboelastograph (TEG), and specific assays of fibrinolysis such as Tissue Plasminogen Activator (TPA) and Plasminogen Activator Inhibitor (PAI-1).

Synonyms

FECLT, FEUCT

Interpretation

Method

Clot Dissolution

Ref. Range Notes

Reference Range: >60 minutes

Ordering & Collection

Specimen Type

Blood

Collection

Patient Preparation:

Prohibit patient from exercising prior to drawing sample.
To avoid release of plasminogen activator, do not massage vein vigorously, pump fist excessively, or leave tourniquet in place for a prolonged period.

Collect: 5 mL blood in BLUE TOP (Sodium Citrate) tube

Expedite transport to the laboratory. Sample must be processed within 30 minutes of collection.

Handling Instructions

Outside Laboratories: Complete processing within 30 minutes of collection. Centrifuge sample for 10 minutes, remove plasma, and centrifuge plasma for another 10 minutes. Transfer 2 mL platelet-poor plasma (minimum 1 mL) to a separate plastic vial and freeze at -60°C to -80°C. Send frozen on dry ice.

Stability: Frozen (Required): 21 days; Refrigerated: 4 hours; Ambient: 30 minutes.

Reject Due To: Gross hemolysis, lipemia, or icteric. Samples received at room temperature or refrigerated.

Quantity

requested: 2 mL Platelet-Poor Plasma
minimum: 1 mL Platelet-Poor Plasma

Processing

UW-MT & HMC Instructions: Forward specimen to Coag Bench for immediate processing. Samples must be processed as described below within 30 minutes of collection.

Login: SEND1-;FREEZE

RSNDT1: MAYNIC
RSTYP1: PLS
RTSRQ1: ;Euglobulin Clot Lysis Time (Mayo Test FEUCT)

Coagulation Bench: Centrifuge sample for 10 minutes, remove plasma, and centrifuge plasma for another 10 minutes. Transfer 2 mL platelet-poor plasma (minimum 1 mL) to a separate plastic vial and freeze at -60°C to -80°C (Sendouts Frozen rack).

Sendouts, order Mayo Test: FEUCT.