Panel on Demand

A targeted bioinformatic masking process is applied to exome sequencing to limit analysis to a user-defined set of genes, effectively creating a custom panel-on-demand. The test includes deletion/duplication (del/dup) analysis for all genes in the selected panel. This method enables customization for a wide range of clinical indications while supporting future broader testing options without the need for resequencing.

We offer several options for panel-on-demand based on the number of genes that will be tested.

• Hyper Panel on Demand (201-500 genes)
• Super Panel on Demand (101-200 genes)
• Mega Panel on Demand (11-100 genes)
• Micro Panel on Demand (2-10 genes)
• Single Gene Sequencing

Use the web tool at https://pod-generator.dlmp.uw.edu/ to generate a 6-character code for a custom panel.

Predefined subpanels are also ordered using the EXPNL test code. Our predefined gene panels include:

Cardiomyopathy Panel: ABCC9, ACTC1, ACTN2, ALPK3, ANKRD1, BAG3, BRAF, CASQ2, CAV3, CAVIN4, CBL, CHRM2, CRYAB, CSRP3, DES, DMD, DOLK, DSC2, DSG2, DSP, DTNA, EMD, FHL1, FHL2, FKTN, FLNC, GAA, GATAD1, GLA, HRAS, ILK, JPH2, JUP, KLHL24, KRAS, LAMA4, LAMP2, LDB3, LMNA, LZTR1, MAP2K1, MAP2K2, MRAS, MYBPC3, MYH6, MYH7, MYL2, MYL3, MYLK2, MYOZ2, MYPN, NEBL, NEXN, NRAS, PDLIM3, PKP2, PLN, PRDM16, PRKAG2, PTPN11, RAF1, RBM20, RIT1, RYR2, SCN5A, SGCD, SHOC2, SOS1, TAFAZZIN, TBX20, TCAP, TMEM43, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TRIM63, TTN, TTR, VCL

Cardiac Arrhythmia Panel: ABCC9, AKAP9, ANK2, CACNA1C, CACNA1D, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, CDH2, DES, DSC2, DSG2, DSP, EMD, FLNC, GJA5, GPD1L, HCN4, JUP, KCNA5, KCND3, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, LDB3, LMNA, MYH6, NKX2-5, NPPA, PKP2, PLN, PPA2, PRKAG2, RBM20, RYR2, SCN1B, SCN2B, SCN3B, SCN4B, SCN5A, SLC4A3, SNTA1, TECRL, TMEM43, TNNT2, TRDN, TRPM4, TTN

Comprehensive Cardiac Arrhythmia/Cardiomyopathy Panel: ABCC9, ACTC1, ACTN2, AKAP9, ALPK3, ANK2, ANKRD1, BAG3, BRAF, CACNA1C, CACNA1D, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV3, CAVIN4, CBL, CDH2, CHRM2, CRYAB, CSRP3, DES, DMD, DOLK, DSC2, DSG2, DSP, DTNA, EMD, FHL1, FHL2, FKTN, FLNC, GAA, GATAD1, GJA5, GLA, GPD1L, HCN4, HRAS, ILK, JPH2, JUP, KCNA5, KCND3, KCNE1, KCNE2, KCNE3, KCNH2, KCNJ2, KCNJ5, KCNJ8, KCNQ1, KLHL24, KRAS, LAMA4, LAMP2, LDB3, LMNA, LZTR1, MAP2K1, MAP2K2, MRAS, MYBPC3, MYH6, MYH7, MYL2, MYL3, MYLK2, MYOZ2, MYPN, NEBL, NEXN, NKX2-5, NPPA, NRAS, PDLIM3, PKP2, PLN, PPA2, PRDM16, PRKAG2, PTPN11, RAF1, RBM20, RIT1, RYR2, SCN1B, SCN2B, SCN3B, SCN4B, SCN5A, SGCD, SHOC2, SLC4A3, SNTA1, SOS1, TAFAZZIN, TBX20, TCAP, TECRL, TMEM43, TNNC1, TNNI3, TNNT2, TPM1, TRDN, TRIM63, TRPM4, TTN, TTR, VCL