Factor II Activity
General Information
Lab Name
Factor II Activity
Lab Code
F2
Epic Name
Factor II Activity
Description
This test is NOT for Factor II Mutation, Factor II DNA or Prothrombin DNA. For Factor II Mutation or Factor II DNA, see: PRODS
Factor II (2) activity is used for diagnosing rare congenital factor II deficiency, investigation of prolonged prothrombin time and evaluating acquired deficiency associated with liver disease or vitamin K dependent factor deficiency. Occasionally, prolonged Prothrombin Time and decreased Factor 2 activity can be seen in patients with lupus anticoagulants or antiphospholipid antibodies with specificity for prothrombin (factor II).
Synonyms
Factor 2
Interpretation
Method
Stago STA Clottable Factor assay
Reference Range
Units: %
| Female | Male | ||
|---|---|---|---|
| Age | Range | Age | Range |
| 0-29d | 33-150 | 0-29d | 33-150 |
| 1m-2m | 34-150 | 1m-2m | 34-150 |
| 3m-5m | 45-150 | 3m-5m | 45-150 |
| 6m- | 50-150 | 6m- | 50-150 |
Effective date: 08/14/2024
Interferences and Limitations
Patients on bivalirudin (Angiomax), dabigatran (Pradaxa), argatroban (Novastan), rivaroxaban (Xarelto), apixaban (Eliquis), and edoxaban (Savaysa) may show prolonged clotting times. This may cause an under- estimation of the factor concentrations.
Ordering & Collection
Specimen Type
Collection
3 or 5 mL BLUE TOP (CITRATE) tube
Forms & Requisitions
Outside clients should fill and submit Coagulation Patient Clinical History Form: Coagulation Patient Clinical History Form
Handling Instructions
The Laboratory MUST process specimen, within 4 hrs of blood collection.
Quantity
requested: entire specimen
Processing
UW-MT Instructions: Take specimen to UW-MT Coag lab for processing. Coag Tech will freeze plasma sample for transport to HMC Coag.
HMC Instructions: Take specimen to HMC Coag lab for processing.
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry ice.
Performance
LIS Dept Code
Coagulation (COAG)
Performing Location(s)
| HMC |
Coagulation
206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420 |
|---|
Frequency
Run Monday-Friday. Reported by end of day.
Available STAT?
No
Billing & Coding
CPT codes
85210
LOINC
Interfaced Order Code
UOW1281
Interfaced Result Code
UOW1281