Factor VIII Inhibitor
General Information
Lab Name
Factor VIII Inhibitor
Lab Code
F8INH
Epic Name
FACTOR VIII INHIBITOR
Description
This assay is only available as part of Factor VIII Inhibitor Reflex Panel (F8INHR).
If the patient is known to be on emicizumab (Hemlibra) drug, F8INH can be ordered by a hematologist or ordering provider.
Synonyms
Chromogenic Factor VIII inhibitor (Bovine-based), F8 inhibitor, Factor 8 inhibitor assay, Factor VIII Bethesda, Factor VIII inhibitor titer, Factor VIII inihibitor level, FVIII inhibitor
Interpretation
Method
Bethesda Assay using chromogenic (2-stage) bovine-based Factor VIII assay
Reference Range
Units: BU
| Female | Male | ||
|---|---|---|---|
| Age | Range | Age | Range |
| 0- | <0.5 | 0- | <0.5 |
Effective date: 12/23/2020
Ordering & Collection
Specimen Type
Collection
3 or 5 mL BLUE TOP (CITRATE) tube
Handling Instructions
The Laboratory MUST process specimen within 4 hours of collection.
Quantity
requested: Entire sample
minimum: 1.0 mL plasma
Processing
Order F8INH if the order is for Factor VIII inhibitor using bovine-based chromogenic reagent. For Porcine Factor VIII inhibitor, see PF8INH.
UW-MT Instructions: Take specimen to UW-MT Coag Lab for processing. Coagulation tech will freeze plasma sample for transport to HMC Coagulation.
HMC Instructions: Take specimen to HMC Coag Lab for processing.
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) at -20°C to -80°C. Send frozen on dry ice.
Performance
LIS Dept Code
Coagulation (COAG)
Performing Location(s)
| HMC |
Coagulation, Special
206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420 |
|---|
Frequency
Run Monday-Friday. Reported by end of day.
Available STAT?
Yes, Monday-Friday 8am-3pm. For other times, contact Lab Medicine resident for approval.
Billing & Coding
CPT codes
85335
LOINC
Interfaced Order Code
UOW2012
Interfaced Result Code
UOW2012