Fibrinogen
General Information
Lab Name
Fibrinogen
Lab Code
FIBCL
Epic Name
Fibrinogen
Description
The fibrinogen activity is a coagulation screening test using the Clauss clotting method to measure the rate of fibrinogen to fibrin conversion under the influence of excess thrombin. The level of fibrinogen in the plasma is used to monitor severity and treatment of DIC, fibrinolysis, advanced liver disease and cirrhosis, acute or chronic inflammatory illnesses, pregnancy or estrogen therapy, and therapy with fibrinolytic agents (e.g streptokinase, tissue plasminogen activator).
Synonyms
Ancrod Fibrinogen, Kinetic Fibrinogen
Interpretation
Method
Stago STA clotting assay (Clauss fibrinogen)
Reference Range
Units: mg/dL
| Female | Male | ||
|---|---|---|---|
| Age | Range | Age | Range |
| 0- | 150-450 | 0- | 150-450 |
Effective date: 01/26/2015
Ref. Range Notes
Note: Present assay measures Kinetic Fibrinogen
Interferences and Limitations
Clinical assay interference and limitations: When the fibrinogen assay is to be performed on samples collected from patients receiving thrombolytic therapy and without addition of an anticoagulant mixture containing a plasmin inhibitor in the collection tube, fibrinogen results may be underestimated. Fibrinogen assay is insensitive to fibrin degradation products (up to 130 ug/mL), hirudin (up to 3 ug/mL) and heparins (UFH and LMWH) (up to 2 IU/mL).
Ordering & Collection
Specimen Type
Collection
3 or 5 mL BLUE TOP (CITRATE) tube Pediatric draws: (At UW-MT ONLY) Contact the lab at 598-6242 and ask for a baby draw tube for coagulation testing.
Handling Instructions
UW-MT/HMC/UW-NW: Laboratory MUST process specimen within 6 hours of blood collection
FHCC: Specimens must be processed within 8 hours of collection.
Quantity
requested: entire sample
Processing
Take specimen to COAG
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send Frozen on dry ice.
Performance
LIS Dept Code
Coagulation (COAG)
Performing Location(s)
| HMC |
Coagulation
206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420 |
|
|---|---|---|
| UW-NW |
Main Lab
206-668-1344 UW Medical Center – Northwest |
|
| FHCC |
Fred Hutch Alliance Lab
206-606-1088 825 Eastlake Ave, Seattle, WA 98109 |
|
| UW-MT |
Coagulation
206-520-4600 Clinical Lab, Room NW220, |
Frequency
Daily
Available STAT?
Yes
Billing & Coding
CPT codes
85384
LOINC
Interfaced Order Code
UOW1685
Interfaced Result Code
UOW1685