SARS CoV 2 Spike Antibody, IgG
General Information
Lab Name
SARS CoV 2 Spike Antibody, IgG
Lab Code
NCVIGQ
Epic Name
SARS-CoV-2 Spike Antibody, IgG
Description
The Abbott Architect SARS-CoV-2 IgG II assay, run under an emergency use authorization from the FDA, is quantitative test designed to detect IgG antibodies to the spike protein of SARS-CoV-2 in serum and plasma from individuals with an adaptive immune response to SARS-CoV-2, indicating recent or prior infection. Results are reported as AU/mL.
Reactive (Positive, ≥50.0 AU/mL) results may be due to immunization or past or present infection with SARS-CoV-2. Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status.
Nonreactive (Negative, <50.0 AU/mL) results do not rule out SARS-CoV-2 infection, particularly in those who have recently been in contact with the virus. Follow-up testing with a molecular diagnostic should be considered to rule out infection in these individuals. Results from antibody testing should not be used as the sole basis to diagnose or exclude SARS-CoV-2 infection or to inform infection status.
For Batteries containing NCVIGQ refer to:
SARS-CoV-2 Antibodies (NCVIGG, NCVIGQ)[NCVIGB], The qualitative detection of anti-Nucleocapsid IgG (NCVIGG) and the quantitative detection of anti-Spike IgG (NCVIGQ) antibodies.
For all questions, contact Client Support Services (available 24/7):
Phone: (206) 520-4600 or (800) 713-5198
Fax: (206) 520-4903
Email: commserv@uw.edu
The test order requisition is available online
Synonyms
SARS-CoV-2 (COVID-19) Antibody, SARS-CoV-2 (COVID-19) Serology
Components
Code | Name |
---|---|
NCIGAU | SARS CoV 2 Spike IgG Quant |
NCIGGR | SARS CoV 2 Spike IgG Result |
NCIGGI | SARS CoV 2 Spike IgG Interp |
Interpretation
Method
Chemiluminesence
Reference Range
See individual components
Ref. Range Notes
Per manufacture’s package insert protective level is ≥50.0 AU/mL.
Guidelines
Ordering & Collection
Specimen Type
Collection
Preferred: 5 mL blood in GOLD SST tube.
Also Acceptable: Orange RST, pearl PPT, serum from red top, plasma from EDTA tube.
Handling Instructions
- Spin within 24 hours and prior to shipment.
- sample is stable for 7 days at 2-8°C once separated from a clot or red blood cells, or in a gel separator tube.
- If testing will be delayed more than 7 days store at -20°C or colder.
Send Specimens to:
UW Medicine
Department of Laboratory Medicine
Virology- Central Testing Lab
1602 Raymond Ave SW
Renton, WA 98057-3356
Tel: (206) 685-6656 opt 4
Quantity
requested: Entire sample
minimum: 0.5 mL serum
Processing
Centrifuge GOLD SST tube and route to Virology Central Lab (Renton).
Centrifuge RED TOP or EDTA tube and aliquot serum/plasma into plastic aliquot tube. Route to Virology Central Lab (Renton).
Stability: Sample stable off the clot, red blood cells, or separator gel for 7 days at 2-8°C. If testing will be delayed more than 7 days store at -20°C or colder.
Performance
LIS Dept Code
Central Lab Virology (RVIR)
Performing Location(s)
CL |
Virology, Renton
206-685-6656 1602 Raymond Ave SW Renton, WA 98057-3356 |
206-685-6656 opt 4 |
---|
Frequency
Mondays and Fridays, with results available on the same day.
Available STAT?
No