Porcine Factor VIII Inhibitor
General Information
Lab Name
Porcine Factor VIII Inhibitor
Lab Code
PF8INH
Epic Name
Porcine Factor VIII Inhibitor
Description
Porcine Factor VIII inhibitor titer is measured to assess the inhibitory activity to recombinant porcine Factor VIII in patients where Obizur® therapy is being considered for the treatment of bleeding. Chromogenic bovine-based Factor VIII reagent is used to measure the residual Factor VIII level and reported in Bethesda Unit.
Synonyms
Porcine F8 Inhibitor, Porcine Factor 8 Inhibitor, Porcine FVIII Inhibitor
Interpretation
Method
Bethesda Assay using chromogenic (2-stage) bovine-based Factor VIII assay
Reference Range
Units: BU
Female | Male | ||
---|---|---|---|
Age | Range | Age | Range |
0- | <0.5 | 0- | <0.5 |
Effective date: 02/01/2021
Ordering & Collection
Specimen Type
Collection
3mL or 5mL BLUE TOP (3.2% Citrated) tube
Handling Instructions
The Laboratory MUST process specimen within 4 hours of collection.
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) at -20° to -80°C. Send frozen on dry ice.
Quantity
requested: Entire sample
minimum: 1.0 mL plasma
Processing
UW-MT Instructions: Take specimen to UW Coagulation Lab for processing. Coagulation tech will freeze plasma sample for transport to HMC Coagulation. If ordered STAT, give to SPS to transport immediately to HMC.
HMC Instructions: Take specimen to Coagulation Lab.
Outside Laboratory: Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) at -20° to -80°C. Send frozen on dry ice.
Performance
LIS Dept Code
Coagulation (COAG)
Performing Location(s)
HMC |
Coagulation
206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420 |
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Frequency
Monday-Friday (8 am-3pm). Sample must be at HMC Laboratory by noon to result the same day.
Available STAT?
Yes. Monday-Friday 8am-3pm. For other times, contact Lab Medicine Resident for approval.
Billing & Coding
CPT codes
85335
LOINC
Interfaced Order Code
UOW4159
Interfaced Result Code
UOW4159