VDRL, CSF (Sendout)
General Information
Lab Name
VDRL, CSF
Lab Code
RCVDRL
Epic Name
VDRL, CSF (Sendout)
External Test Id
0050206
Description
Test Information: The Venereal Disease Research Laboratory (VDRL) is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies. The presence of neurosyphilis in untreated patients can be detected by the presence of pleocytosis, elevated protein, and a positive VDRL.
Useful For: Aiding in the diagnosis of neurosyphilis.
Test Algorithm: If the VDRL is weakly reactive or reactive, a titer will be performed at additional charge.
***Order Alert: Effective 05/22/2025, this test is no longer available at Mayo Clinic Laboratories. Samples will be forwarded to ARUP Laboratories for test Treponema pallidum (VDRL), Cerebrospinal Fluid with Reflex to Titer and reported under Reference Laboratory Test 1 (SEND1).***
Synonyms
0050206, Neurosyphilis, RPR-CSF, Soft-VDSF, Syphilis, VDSF
Components
Code | Name |
---|---|
CVD | VDRL, CSF |
Interpretation
Method
Semi-Quantitative Flocculation
Reference Range
See individual components
Ref. Range Notes
Reference Interval: | Nonreactive |
Ordering & Collection
Specimen Type
Collection
0.5 mL CSF in a sterile vial
Handling Instructions
Outside Laboratories: Freeze 0.5 mL CSF in a plastic vial at -20°C.
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Quantity
requested: 0.5 mL CSF
minimum: 0.4 mL CSF
Processing
Freeze 0.5 mL CSF in a plastic vial at -20°C.
Sendouts:
- Temporary Workflow: Order ARUP Test: 0050206 (ARUPConnect manual order)
- CAST will add a SEND1 in Sunquest upon result receipt.
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.
Performance
LIS Dept Code
Sendouts Mayo Lab (FZ) (MAFZ)
Performing Location(s)
Sendout |
ARUP Laboratories, Inc.
800-522-2787 500 Chipeta Way |
---|
Frequency
Performed: Sunday through Saturday. Reported: 1-4 days from sample receipt at ARUP Laboratories.
Available STAT?
No
Billing & Coding
CPT codes
86592
Billing Comments
If this test is reactive or weakly reactive, a VDRL titer will be performed at additional charge.
LOINC
Interfaced Order Code
UOW4104