VDRL, CSF

General Information

Lab Name

VDRL, CSF

Lab Code

RCVDRL

Epic Name

VDRL, CSF (Sendout)

External Test Id

VDSF

Description

The Venereal Disease Research Laboratory (VDRL) is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies. The presence of neurosyphilis in untreated patients can be detected by the presence of pleocytosis, elevated protein, and a positive VDRL.

Useful For: Aiding in the diagnosis of neurosyphilis.

Note: If this test is positive, VDRL titer will be performed at an additional charge.

Mayo Clinic Laboratories: Clinical & Interpretive Information for VDRL, Spinal Fluid

Synonyms

Neurosyphilis, RPR-CSF, Soft-VDSF, Syphilis, VDSF

Components

Code Name
CVD VDRL, CSF

Interpretation

Method

Floculation/Agglutination

Reference Range

See individual components

Ordering & Collection

Specimen Type

CSF, Cerebrospinal Fluid, Spinal Fluid

Collection

Collect 0.5 mL CSF in a sterile vial.

Quantity

requested: 0.5 mL CSF
minimum: 0.2 mL CSF

Processing

Freeze 0.5 mL CSF at -20°C.

Sendouts, order Mayo Test: VDSF

Stability: Frozen (preferred): 14 days; Refrigerated: 14 days; Ambient: Unacceptable.

Reject Due To:

  • Gross hemolysis
  • Gross lipemia

Performance

LIS Dept Code

Sendouts Mayo Lab (FZ) (MAFZ)

Performing Location(s)

Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-1710

3050 Superior Drive NW
Rochester, MN 55901

Frequency

Performed: Monday through Friday; 12 p.m. Analytic Time: 1 day.

Available STAT?

No

Billing & Coding

CPT codes

86592

Billing Comments

If this test is positive, VDRL titer will be performed at an additional charge.

LOINC

5290-2

Interfaced Order Code

UOW4104