Protein S, Total Antigen (Sendout)
General Information
Lab Name
Protein S, Total Antigen (Sendout)
Lab Code
RPSAGT
Epic Name
Protein S, Total Antigen (Sendout)
External Test Id
0030112
Description
Ordering Recommendation: Use to subtype deficiency in known protein S-deficient individuals in combination with Protein S Antigen (Free) [PSAGF] or Protein S, Functional.
Patient Preparation: Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Synonyms
0030112, S Protein Antigen, Total Protein S Antigen
Components
| Code | Name |
|---|---|
| RPSATR | Protein S Antigen Total Result |
Interpretation
Method
Microlatex Particle-Mediated Immunoassay
Reference Range
See individual components
Ref. Range Notes
Reference Interval:
| Age | Male | Female |
| 1-4 days: | 12-60% | 12-60% |
| 5-29 days: | 22-78% | 22-78% |
| 30-89 days: | 33-93% | 33-93% |
| 90-179 days: | 54-118% | 54-118% |
| 180-364 days: | 55-119% | 55-119% |
| 1-5 years: | 54-118% | 54-118% |
| 6-10 years: | 41-114% | 41-114% |
| 11 years and older: | 84-134% | 63-126% |
Interferences and Limitations
Cautions: Patients on warfarin may have decreased protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of protein S.
Ordering & Collection
Specimen Type
Collection
6 mL Blood in BLUE TOP (sodium citrate) tube
Handling Instructions
Outside Laboratory:
- Centrifuge for 10 minutes and remove plasma.
- Centrifuge the plasma again for another 10 minutes.
- Transfer 1.5 mL platelet-poor plasma (1 mL minimum) into a separate plastic aliquot. Freeze plasma at -20°C to -80°C while awaiting shipment. Transport on dry ice.
Critical Frozen: Submit separate specimens when ordering multiple tests.
Stability: Frozen (-20°C): 3 months; Frozen (-70°C): 6 months; Refrigerated: Unacceptable; Ambient: 4 hours.
Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.
Quantity
requested: 1.5 mL platelet-poor plasma
minimum: 1 mL platelet-poor plasma
Processing
UW-MT SPS: Immediately forward specimens to Coagulation Lab for processing.
UW-MT Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma (1 mL minimum) into a separate plastic aliquot. Freeze plasma at -20°C (place in the UW Sendouts frozen rack).
HMC SPS: Immediately forward specimens to Coagulation Lab for processing.
HMC Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma (1 mL minimum) into a separate plastic aliquot. Freeze plasma at -20°C. Forward to UW-MT for sendout.
UW-NW or Fred Hutch: Centrifuge for 10 minutes and remove plasma. Centrifuge the plasma again for another 10 minutes. Transfer 1.5 mL (1 mL minimum) platelet-poor plasma into a separate plastic aliquot. Freeze plasma at -20°C. Forward to UW-MT for sendout.
Sendouts:
- Order ARUP Test: 0030112.
- Interfaced: Yes. [Interface: 602; Department: ARPZ]
Stability: Frozen (-20°C): 3 months; Frozen (-70°C): 6 months; Refrigerated: Unacceptable; Ambient: 4 hours.
Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.
Performance
LIS Dept Code
Sendouts ARUP Lab (FZ) (ARPZ)
Performing Location(s)
| Sendout |
ARUP Laboratories, Inc.
800-522-2787 500 Chipeta Way |
|---|
Frequency
Performed: Sunday through Saturday. Reported: 1-2 days from sample receipt at ARUP Laboratories.
Available STAT?
No