Trypanosoma cruzi IgG Antibody (Sendout)
General Information
Lab Name
Trypanosoma cruzi IgG Antibody (Sendout)
Lab Code
RTRYPG
Epic Name
Trypanosoma cruzi IgG Antibody (Sendout)
External Test Id
0051076
Description
Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).
Ordering Guidance: Secondary serologic test for the diagnosis of Trypanosoma cruzi infection. The preferred initial test is RCHAGS (Trypanosoma cruzi Total Antibody, Sendout) to Mayo Clinic Laboratories. The CDC recommends performing 2 independent tests for the serologic diagnosis of Chagas disease¹.
References
- Centers for Disease Control and Prevention (CDC): Laboratory Diagnosis of American Trypanosomiasis
Synonyms
0051076, American trypanosomiasis, Chagas Antibody IgG, Chagas Disease, T. cruzi, Tcruzi IgG Ab, Trypanosomiasis
Components
| Code | Name |
|---|---|
| RTRYPR | Trypanosoma cruzi IgG Antibody |
Interpretation
Method
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Reference Range
See individual components
Ref. Range Notes
Reference Interval: <=1.0 IV
Interpretation:
| <=1.0 IV: |
Negative - No significant level of Trypanosoma cruzi IgG antibody detected. |
| 1.1 IV: |
Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful. |
| >=1.2 IV: | Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection. |
Interferences and Limitations
Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.
Guidelines
Ordering & Collection
Specimen Type
Collection
3 mL blood in GOLD TOP SST or RED TOP tube
Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Quantity
requested: 0.5 mL serum
minimum: 0.3 mL serum
Processing
Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.
Sendouts:
- Order ARUP Test: 0051076.
- Interfaced: Yes. [Interface Number: 602; Department: ARPR]
Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Performance
LIS Dept Code
Sendouts ARUP Lab (RF) (ARPR)
Performing Location(s)
| Sendout |
ARUP Laboratories, Inc.
800-522-2787 500 Chipeta Way |
|---|
Frequency
Performed: Wednesday. Reported: 1-8 days.
Available STAT?
No