Trypanosoma cruzi IgG Antibody (Sendout)

General Information

Lab Name

Trypanosoma cruzi IgG Antibody (Sendout)

Lab Code

RTRYPG

Epic Name

Trypanosoma cruzi IgG Antibody (Sendout)


Order using Lab Undefined Order [LABUND]

External Test Id

0051076

Description

Useful For: Aiding in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).

    Ordering Requirements: Orders must be approved by the Laboratory Medicine Resident (LMR) or Microbiology fellow on-call.

      Ordering Guidance: The preferred first-line test is Trypanosoma cruzi Antibody Panel (Sendout) [RCRUZI]. If results from the Mayo panel are discordant, this test to ARUP may be used as a tie-breaker, although it is less sensitive than other options. Consider alternative testing available at Eurofins Viracor, with guidance from the LMR or Micro fellow.

      Synonyms

      0051076, American trypanosomiasis, Chagas Antibody IgG, Chagas Disease, T. cruzi, Tcruzi IgG Ab, Trypanosomiasis

      Components

      Code Name
      RTRYPR Trypanosoma cruzi IgG Antibody

      Interpretation

      Method

      Semi-Quantitative Enzyme-Linked Immunosorbent Assay

      Reference Range

      See individual components

      Ref. Range Notes

      Reference Interval: <=1.0 IV

      Interpretation:

      <=1.0 IV:

      Negative - No significant level of Trypanosoma cruzi IgG antibody detected.
      1.1 IV:

      Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
      >=1.2 IV: Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection.

      Interferences and Limitations

      Cautions: This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.

      Guidelines

      Ordering & Collection

      Specimen Type

      Blood

      Collection

      3 mL blood in GOLD TOP SST or RED TOP tube

      Approval Required

      Laboratory Medicine Resident (LMR) or Microbiology Fellow approval is required.

      Handling Instructions

      Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

      Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

      Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

      Quantity

      requested: 0.5 mL serum
      minimum: 0.3 mL serum

      Processing

      Centrifuge sample and transfer serum to a separate plastic vial within two hours of collection. Refrigerate serum.

      Sendouts:

      • Order ARUP Test: 0051076.
      • Interfaced: Yes. [Interface Number: 602; Department: ARPR]

      Stability: Frozen: 1 year; Refrigerated: 2 weeks; Ambient: 48 hours.

      Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

      Performance

      LIS Dept Code

      Sendouts ARUP Lab (RF) (ARPR)

      Performing Location(s)

      Sendout ARUP Laboratories, Inc.
      800-522-2787

      500 Chipeta Way
      Salt Lake City, UT 84108

      Frequency

      Performed: Wednesday. Reported: 1-8 days.

      Available STAT?

      No

      Billing & Coding

      CPT codes

      86753

      LOINC

      59387-1