Serologic Syphilis Screen
General Information
Lab Name
Serologic Syphilis Screen
Lab Code
SYPHSC
Epic Name
Syphilis Screen
Description
Samples that are screened at borderline/reactive will be sent to the state lab for supplemental testing.
To diagnose congenital syphilis in neonate/infants and to monitor treatment responses, quantitative RPR testing should be performed instead of the serologic syphilis screen. For congenital syphilis diagnosis, concurrent quantitative RPR testing of maternal serum should be obtained, to enable comparison between neonatal and maternal RPR titers.
Synonyms
reagin, RPR, SYPHS, Treponema pallidum
Components
| Code | Name |
|---|---|
| SYPHT | T. pallidum IgG/IgM Ab (Bioplex) |
| RPRSCB | RPR Screen |
| SYPHSI | Syphilis Screening Status |
Interpretation
Method
Multiplex immunoassay
Reference Range
See individual components
Guidelines
Ordering & Collection
Specimen Type
Collection
Preferred: 6 mL blood in GOLD SST Tube
Also Acceptable: RED TOP
Plasma can only be used if a serum sample is not available and the use of plasma has been approved by the Lab Medicine Resident. Note: if screening results are not negative, a serum sample will need to be drawn for the mandatory State Lab supplemental testing, leading to reporting delays.
Unacceptable: Green, Lavender, Orange RST or Blue Top tube.
Handling Instructions
Stability: Refrigerated: 14 days (preferred); Frozen at -20°C or colder: Long Term (avoid repeated freeze-thaws)
Quantity
requested: 2 mL serum
minimum: 1.2 mL serum
Processing
Refrigerate serum
STAT requests need approval from Lab Medicine Resident on call
Performance
LIS Dept Code
Immunology (IMM)
Performing Location(s)
| UW-MT |
Immunology
206-520-4600 Clinical Lab, Room NW220, |
|---|
Frequency
Monday-Friday
Available STAT?
No