Porphobilinogen Quantitative, Random urine

General Information

Lab Name

Porphobilinogen, Urine

Lab Code

UPBGR

Epic Name

PORPHOBILINOGEN QNT, RAND URN

Description

STAT requests require approval from Lab Med Resident. Increased urinary porphobilinogen concentration in the presence of acute clinical symptoms is consistent with a biochemical diagnosis of acute porphyria, variegate porphyria, or hereditary coproporphyria. Normal concentrations may be seen in porphyria patients who are asymptomatic at the time of collection. Porphyria Foundation Website

Synonyms

porphyria, spot urine

Interpretation

Method

Modified Mauzerall-Granick method

Reference Range

Units: mg/L

Female		Male
Age	Range	Age	Range
0-	0.0-2.3	0-	0.0-2.3

Effective date: 08/01/2011

Ref. Range Notes

The literature reference for this reference range is: Deacon AC, Elder GH. Front line tests for the investigation of suspected porphyria. J Clin Pathol 2001; 54:500-507.

Ordering & Collection

Specimen Type

Urine

Collection

RANDOM URINE: STAT specimens do not need preservative if delivered immediately to the laboratory. Protect specimen from light.

RANDOM URINE: To ROUTINE specimens add approximately 5 g sodium bicarbonate for 30 mL or more urine (1 well rounded tsp). Add less sodium bicarbonate for volumes less than 30 mL. Protect specimen from light.

For 24-hour urine, see Porphobilinogen Quantitative, 24-h urine (UPBG)

Quantity

requested: 50 mL urine
minimum: 10 mL urine

Processing

Mix well. Refrigerate in a dark bottle.

Performance

LIS Dept Code

Chemistry, Harborview (CHH)

Performing Location(s)

HMC	Chemistry, Special 206-520-4600 325 9th Ave, Rm # GWH-47, Seattle, WA 98104-2420

Frequency

Monday to Friday, samples received in Special Chemistry by 11AM. Weekends and holidays, approved STAT only.

Laboratory Test Guide