Pathology Presents: Functional analysis of brain circuits affected in Parkinson’s disease

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Speaker

Martin Darvas, PhD
Acting Assistant Professor
Department of Pathology
University of Washington

Faculty Sponsor

Christine Disteche, PhD


Date & Time

October 12, 2016 at 4:30pm - 5:30pm

Location

Health Sciences Building, T-739


Description

Why Attend?

Functional analysis of brain circuits affected in Parkinson’s disease

The focus of Dr. Darvas’ research is on identifying brain circuits and neurotransmitter systems that are relevant for basic mechanisms of learning, memory and decision making, and for cognitive impairment in Parkinson’s disease. Our goal is to define key neurotransmitter systems and brain areas and thereby identify new potential therapeutic targets. In addition, we investigate the interaction between neurotransmitter systems that are affected in Parkinson’s disease and thereby create more disease models that more accurately reflect the complexity of neurodegenerative disease. The Darvas Laboratory addresses these prevalent, urgent questions through experimental studies that utilize a combination of mouse genetics, viral gene transfer, behavioral, pharmacological, biochemical and histological techniques. Furthermore, we test hypotheses concerning specific mechanisms of neuron injury and how these are relevant for pathological processes in Parkinson’s disease.