October 2015

  • Path Grand Rounds 12:00 pm - 1:00 pm   Curriculum Renewal 2015. The Why, How, When, and What We Need To Do About It

    Mara Rendi, MD, PhD, Assistant Professor, Department of Pathology, University of Washington

    Location: UWMC NE110 Conference Room

    Summary: To learn about the changes underway in the new curriculum at the University of Washington School of medicine. We shall discuss the theory behind the new curriculum, the impact this will have on pathology education, and what we as pathologists can do to best educate the incoming medical students and expose them to our specialty.

  • Earl P. Benditt Endowed Lectureship 4:30 pm - 5:30 pm   Protein Damage: Biological Consequences and Role in Disease Pathogenesis

    Miroslav Radman, PhD, Founder and Research Director, Mediterranean Institute for Life Sciences, Split, Croatia, Professor Emeritus, University of Paris - R. Descartes Medical School, Paris, France

    Location: Health Sciences Building, T-739

    Summary: We recently found that oxidative damage to proteins can cause both reversible as well as long-lived phenotypic consequences, and that irreversible forms of radiation-induced oxidative damage to proteins such as carbonylation are a better predictor of cell survival than is radiation-induced DNA damage.

  • Genetic Approaches to Aging Trainee Research Presentations 2:30 pm - 4:00 pm   Alessandro Bitto and Jason Pitt

    Alessandro Bitto, PhD and Jason Pitt, PhD, Post-Doctoral Fellows, Kaeberlein Lab, Department of Pathology, University of Washington

    Location: Foege N-130

  • Annual Alvord Lecture 4:30 pm - 5:30 pm   Implementing Molecular Parameters in the World Health Organization Classification of CNS Tumors

    David Louis, MD, Benjamin Castleman Professor of Pathology, Department of Pathology, Harvard Medical School

    Location: Health Science Building, T-739

    Summary: David N. Louis, MD, is the Benjamin Castleman Professor of Pathology at Harvard Medical School and pathologist-in-chief at Massachusetts General Hospital.

  • Pathology Presents 4:30 pm - 5:30 pm   Everybody Needs a “Brake”: Role of Immunological Brakes in T cell Immunity

    Surojit Sarkar, PhD, Assistant Professor, Department of Pediatrics, University of Washington School of Medicine, Principal Investigator, BTCCCR, Seattle Children's Research Institute

    Location: Health Sciences Building, Room T-739

    Summary: Our immune system has a lot of similarities to a speeding automobile with a gas and a brake pedal. Just like a speeding car uses brakes to slow down and ensure a safer ride, our immune system also has built-in brakes that continuously work to ensure that our immune responses are adequately slowed down for preserving long-term immunity to pathogens, tumors and vaccines.

  • Pathology Presents 4:30 pm - 5:30 pm   Genetic, Molecular, and Chemical Approaches to Dissect UV-Induced DNA Damage Responses

    Masaoki Kawasumi, MD, PhD, Acting Assistant Professor, Division of Dermatology, University of Washington

    Location: Health Sciences Building, Room T-739

    Summary: Ultraviolet (UV) from one-hour of sunlight generates 100,000 DNA lesions per cell that are potentially mutagenic, leading to the most prevalent cancers in humans. Understanding how cells respond to UV-induced DNA lesions could be helpful to selectively kill DNA-damaged cells and prevent UV-associated skin cancers.

  • Doctoral Dissertations 4:30 pm - 5:30 pm   Examination of Proteome Turnover in Mouse Aging: In Vivo Studies by Stable Isotope MS

    Nate Basisty, Graduate Student, Department of Pathology, University of Washington

    Location: UW Medicine South Lake Union, Orin Smith Auditorium