Stephen C. De Rosa, MD

Research Professor

Stephen C. De Rosa, MD


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Clinical and Research Background

Dr. De Rosa has worked with the HIV Vaccine Trials Network (HVTN) for the past eight years, and leads the flow cytometry laboratory. In this role, he oversees the operation and maintenance of the flow cytometer analyzers and sorters, directly supervises HVTN Research & Development technicians in the development and optimization of new flow cytometry-based assays, and consults with the Endpoints Laboratory manager concerning the performance and analysis of the validated flow cytometric assays conducted on clinical trial samples. Following graduation from medical school and some brief clinical training, he has pursued a full-time career in basic and applied research. He trained as a postdoctoral fellow in the Herzenberg Laboratory at Stanford, the laboratory that first developed flow cytometry technology 40 years ago. He then continued his training with Mario Roederer, an internationally-recognized flow expert, at the NIH Vaccine Research Center (VRC). While at the VRC, he implemented intracellular cytokine staining assays for evaluation of vaccine-induced T cells. He later implemented and validated similar assays within the HVTN. He is internationally recognized for this work in implementing and validating functional assays using cutting-edge technology for high throughput analysis of clinical trial samples.

Research Interests

T-cell immunogenicity to candidate HIV vaccines

Flow cytometric technology and data analysis

Education and Training

Research Fellow, Vaccine Research Center, NIH, Bethesda, MD, 2000-2004

Postdoctoral Fellow, Stanford University School of Medicine, Stanford, CA, 1994-2000

Pediatric Intern, Kaiser Permanente Hospital, San Francisco, CA, 1993-1994

Pediatric Intern, Stanford University Hospital, Stanford, CA, 1990-1991

MD Stanford University School of Medicine, Stanford, CA, 1990

BS Chemical Engineering, Columbia University, New York, NY, 1983


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