Anna K. Gillespie, PhD

Assistant Professor

Anna K. Gillespie, PhD

Pronouns:

She, her

E-mail:

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Office Location:

HSB - Room F-506B

Mailing Address:

Box 357420
1959 NE Pacific St
Seattle, WA 98195‐7110

Research Lab

Gillespie Lab


Clinical and Research Background

The Gillespie Lab strives to understand how the neural mechanisms underlying memory processes degrade over the course of healthy aging and in the context of neurodegenerative disease. The lab uses in vivo electrophysiology to record simultaneously from hundreds of hippocampal neurons in rats as they learn and perform complex memory-dependent tasks. We use advanced computational approaches to evaluate how neural populations encode ongoing experience and store such experience as memory. We can then identify how changes in these processes lead to impairments in memory-guided behavior in aged animals and in rat models of Alzheimer’s disease. We are working to develop novel interventional tools to prevent or reduce detrimental changes in neural activity and preserve cognitive ability throughout the lifespan.

Research Interests

Learning and memory, In vivo electrophysiology, rodent models of Alzheimer’s disease, aging

Academic and Medical Appointments

Assistant Professor, Departments of Biological Structure and Lab Medicine and Pathology, University of Washington, Seattle, WA 2023-present

Education and Training

Postdoctoral Fellowship, Department of Physiology, University of California, San Francisco, 2015-2022

PhD in Biomedical Sciences, University of California, San Francisco, 2010-2015

BS in Biology, Stanford University, 2006-2010

Publications

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