Joseph D. Powers, PhD

Assistant Professor

Joseph D. Powers, PhD


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Office Location:

Brotman Building, Room 335

Mailing Address:

Box 358050
850 Republican St
Seattle, WA 98109

Research Lab

Powers Lab

Clinical and Research Background

Dr. Powers is a faculty member of the UW Center for Cardiovascular Biology on the South Lake Union campus. Research in the Powers Lab is centered around understanding cellular and molecular mechanisms underlying various forms of heart diseases, with a focus on multi-scale biomechanics, mechanobiology, and biological structure. During each heartbeat, cardiac muscle cells (cardiomyocytes) experience a myriad of mechanical forces that originate from both within and outside of the cells. These forces are transmitted as mechanical signals between and within cardiomyocytes, where biological structures transduce them into responses that can affect numerous physiological processes from cell electrophysiology to cardiac contractility to hypertrophy. The Powers Lab integrates computational and experimental approaches using engineered rodent models and human stem cell-derived cardiomyocytes to reveal mechanosignaling pathways that are involved in cardiac dysfunction and remodeling, with the greater goal of informing the development of new therapies to treat heart diseases.

Academic and Medical Appointments

Assistant Professor, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 2023-Present

Assistant Professor, Department of Mechanical Engineering, University of Washington, Seattle, WA, 2023-Present

Education and Training

Postdoctoral Fellow, Bioengineering, University of California San Diego, La Jolla, CA, 2018-2023

PhD, Bioengineering, University of Washington, Seattle, WA, 2013-2018

MS, Biomedical Engineering, University of Minnesota, Minneapolis, MN, 2012-2013

BS, Biomedical Engineering (dual-degree program), University of Minnesota, Minneapolis, MN, 2010-2012

BS, Physics (dual-degree program), University of Wisconsin La Crosse, La Crosse, WI, 2007-2012


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