Images of Barrett’s esophagus Indefinite for Dysplasia

We use the term "indefinite for dysplasia" when we are in doubt of the significance of the epithelial abnormalities present in a biopsy. Examples of situations when we use this diagnosis are provided below.

Active inflammation in area mimicking dysplasia.

Nuclear stratification without obvious dysplastic features.

Highly atypical glands with no overlying epithelium for evaluation.

An area adjacent to an ulcer.  The epithelium is highly atypical, but given the proximity to an ulcer, we would interpret these changes as indefinite for dysplasia


Additional examples of cases we would interpret as indefinite for dysplasia.