Laboratory Test Guide

Lyme CNS Infection IgG with reflex to Antibody Index

General Information

Lab Name

Lab Code

892

Description

This test aids in the diagnosis of neuroinvasive Lyme disease or neuroborreliosis due to Borrelia species associated with Lyme disease (eg, B burgdorferi, B garinii, B afzelli). If the screen is reactive, then the antibody index is performed at an additional charge. Note: This test requires both CSF and blood, collected within 24 hours of each other. Mayo Lyme Neuroborreliosis Diagnostic Algorithm

Synonyms

Borrelia species, LNBAB, Lyme CNS Disease, Neuroborreliosis, Neuroinvasive Lyme Disease

Interpretation

Method

Enzyme-Linked Immunosorbent Assay (ELISA)

Guidelines

Ordering & Collection

Specimen Type

CSF [Cerebrospinal Fluid] & Blood

Collection

1.5 mL Spinal Fluid + 5mL blood in RED TOP tube or GOLD TOP (SST)

Note: Blood and CSF samples must be collected within 24 hours of each other.

Quantity

requested: 1.5 mL CSF + 1.5 mL Serum
minimum: 1.2 mL CSF + 1.2 mL Serum

Processing

CSF: Refrigerate sample.
Blood: Centrifuge sample; transfer serum to a separate vial and refrigerate.
 
Login: SEND1-;REFRIG
RSNDTO: MAYOSD
RSPTYP: CSF-SRM
RTSTRQ: ;Lyme CNS Infection IgG with AI Reflex (Mayo Test LNBAB)

Sendouts, order Mayo Test: LNBAB. Write the sample type (CSF or Serum) on the aliquot tubes and band them together.

Stability: Refrigerated (Preferred): 11 days; Frozen: 35 days; Ambient: Unacceptable.

Performance

LIS Dept Code

Performing Location(s)

HMC Sendout
UW-MT Sendout

Other Locations/Notes

MAYOSD Mayo Medical Laboratories 3050 Superior Drive NW Rochester, MN 55901 1-800-533-1710

Frequency

Performed: Monday, Wednesday, Friday at 08:00 am. Maximum Laboratory Time: 4 days.

Available STAT?

No

Billing & Coding

CPT codes

Billing Comments

CPT Codes: Lyme CNS IgG Screen: 86618; Lyme CNS IgG Antibody Index, if performed: 86317x2, 82784x2, 82042

LOINC