Laboratory Test Guide

Hepatitis B Antibodies (HBcAB, HBsAB)

General Information

Lab Name

Hepatitis B Ab

Lab Code

HBAB

Epic Name

Hepatitis B Antibody

Description

A Battery of tests for Hepatitis B virus markers in human sera by the FDA approved Abbott ARCHITECT chemiluminescent immunoassays.

Quantitative detection of Hepatitis B virus Surface IgG antibody (HBSAb). Result are reported as mIU/mL.
Qualitative detection of Hepatitis B virus Core IgG and IgM antibodies (HBCAb)

For ordering individual battery components:

HBSAb, see Hepatitis B Surface Antibody (HBsAb) [HBSA]

HBCAb, see Hepatitis B Core Antibody (HBcAb) [HBCA]

Synonyms

HAB

Components

Code	Name
BSAB	Hepatitis B Surface Ab
IUAB	Hepatitis B Surf Ab Intl Units
BCAB	Hepatitis B Core Ab
IN32	Hepatitis B Ab Interp

Interpretation

Method

Chemiluminescence Immunoassay

Reference Range

See individual components

Ref. Range Notes

Per manufacture’s package insert protective level of HBSAb is ≥12 mIU/mL.

Ordering & Collection

Specimen Type

Blood

Collection

Blood: 5 mL blood in GOLD TOP serum separator tube (SST).

Also acceptable: 5 mL blood in ORANGE TOP rapid serum tube (RST) or RED TOP tube

Quantity

requested: 1 mL serum
minimum: 0.5 mL serum

Processing

Blood: Specimens may be stored on or off the clot, red blood cells, or separator gel for up to 3 days at room temperature (15-30°C) or up to 7 days at 2-8°C. If testing will be delayed more than 3 days for specimens stored at room temperature or more than 7 days for specimens stored at 2-8°C, remove serum from the clot, red blood cells, or separator gel and store at -20°C or colder. Avoid more than three freeze/thaw cycles.

Outside Laboratories: Specimens may be stored on or off the clot, red blood cells, or separator gel for up to 3 days at room temperature (15-30°C) or up to 7 days at 2-8°C. If testing will be delayed more than 3 days for specimens stored at room temperature or more than 7 days for specimens stored at 2-8°C, remove serum from the clot, red blood cells, or separator gel and store at -20°C or colder. Avoid more than three freeze/thaw cycles.

Unacceptable samples: Cord blood, neonatal specimens, cadaver specimens, heat-inactivated specimens, or body fluids such as saliva, urine, amniotic fluid, or pleural fluid. Specimens with obvious microbial contamination or are grossly hemolyzed.

Performance

LIS Dept Code

Clinical Virology (CVIR)

Performing Location(s)

Other	Virology, Eastlake 206-685-6656 Virology Laboratory, Ste 320 1616 Eastlake Ave E. Seattle, WA 98102