Fungal DNA Detection by ITS Next Gen Seq

General Information

Lab Name

Fungal DNA Detection by ITS Next Gen Seq

Lab Code

NGSITS

Epic Name

(not orderable in Epic)

Description

Fungal ITS Next Generation Sequencing is only available as reflexive test from Fungal PCR reflex NGS [FUNDNA] when there is evidence of multiple fungal templates present.

Results in 10 business days after reflex from Fungal PCR reflex NGS [FUNDNA]

Broad range PCR and Sanger sequencing can be used to perform accurate genus- or species-level taxonomic assignment for several fungal gene targets. Unfortunately, when PCR amplification is performed on polymicrobial specimens, the presence of multiple templates causes interference during Sanger sequencing such that results are generally uninterpretable. In contrast, next-generation sequencing methods provide individual sequence data for large numbers of DNA templates, allowing each to be classified independently. This permits fungal species identification for samples from which usable data cannot be obtained by conventional clinical methods.

Synonyms

broad range fungal PCR, broad range fungi PCR, fungal identification, fungal ITS, Fungal PCR, fungal sequencing, Fungi PCR, fungi sequencing, ITS deep sequencing, ITS PCR, ITS sequencing, molecular fungal, molecular fungi, Next Generation Sequencing, NGS, polymicrobial sequencing, universal fungal PCR, universal fungi PCR

Components

Code Name
NGITSI Fungal ITS Gene Next Gen Seq Specimen
NGITRS Fungal ITS Gene Next Gen Seq Results
NGITIN Fungal ITS Gene Next Gen Seq Interpretation
NGITSR Fungal ITS Gene Next Gen Seq Requests
NGITME Fungal ITS Gene Next Gen Seq Method Note

Interpretation

Method

DNA extraction, nucleic acid purification, polymerase chain reaction (PCR), sequencing

Reference Range

See individual components

Guidelines

Ordering & Collection

Specimen Type

This only available as a reflexive test, please refer to Fungal DNA Detection by PCR (FUNDNA).

Collection

Processing

This only available as a reflexive test, please refer to Fungal PCR reflex NGS [FUNDNA].

Performance

LIS Dept Code

Micro Molecular Diag (MMD)

Performing Location(s)

CL Molecular Microbiology
206-598-5735

Shipping Address

Attn: Molecular Microbiology
UW CLSPS
1601 Lind Ave SW
Room 171A
Renton, WA 98057

Performing Lab Address

UW Medicine Central Laboratory
Molecular Microbiology
1601 Lind Ave SW
Room 485
Renton, WA 98057

We receive specimens 7 days a week, 365 days a year.

Please e-mail us with any questions or comments you have, so that we can provide you with the best possible service. Our e-mail is monitored in real time, and your inquiry will be answered as soon as possible.

e-mail: molmicdx@uw.edu

For urgent inquiries, billing inquiries, or requests for faxed reports, please contact our Client Services Department at (206) 598-5735 or (800) 713-5198.

Frequency

Available STAT?

No

Billing & Coding

CPT codes

87801

LOINC

91090-1

Interfaced Order Code

UOW4626