Dengue Fever IgG and IgM Antibody (Sendout)

General Information

Lab Name

Dengue Fever IgG and IgM Antibody (Sendout)

Lab Code

RDFAGM

Epic Name

Dengue Fever IgG and IgM Antibody (Sendout)

External Test Id

0093096

Description

Ordering Recommendation: May aid in the diagnosis of dengue when timing of infection is uncertain. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Collection Note: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Specimens must be plainly marked as "acute" or "convalescent."

Synonyms

0093096, Arbovirus, DENGUE AB, Dengue Fever Ab Panel, Dengue Fever Antibodies, Flavivirus

Components

Code Name
RDFAGR Dengue Fever IgG Antibody
RDFAMR Dengue Fever IgM Antibody

Interpretation

Method

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Reference Range

See individual components

Ref. Range Notes

Dengue Fever Virus Antibody, IgG:

Value: Interpretation:
1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.

Dengue Fever Virus Antibody, IgM:

Value: Interpretation:
1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Guidelines

Ordering & Collection

Specimen Type

Blood

Collection

Collect 3 mL blood in GOLD SST or RED TOP tube

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Quantity

requested: 1 mL serum
minimum: 0.1 mL serum

Processing

Centrifuge sample and transfer serum to a separate plastic vial within 2 hours of collection. Refrigerate serum.

Sendouts:

  • Order ARUP Test: 0093096.
  • Interfaced: Yes. [Interface Number: 602; Department: ARPR]
  • If parallel testing will be performed:
    • Mark serum samples as "acute" or "convalescent," as appropriate. Convalescent samples must be received by ARUP within 30 days from receipt of the acute sample.
    • For the convalescent order, enter instructions in the modifier before batching sample. Comment: Run parallel testing with acute sample collected (MM/DD/YY).

Stability: Refrigerated (preferred): 2 weeks; Frozen: 1 year; Ambient: 48 hours. Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Performance

LIS Dept Code

Sendouts ARUP Lab (RF) (ARPR)

Performing Location(s)

Sendout ARUP Laboratories, Inc.
800-522-2787

500 Chipeta Way
Salt Lake City, UT 84108

Frequency

Performed: Monday, Wednesday, Friday. Reported: 1-5 days.

Available STAT?

No

Billing & Coding

CPT codes

86790x2

LOINC

41878-0

Interfaced Order Code

UOW4948