Rubella Immune Status Viral Serology
General Information
Lab Name
Rubella Immune Status
Lab Code
RUIS
Epic Name
Rubella Immune Status
Description
The FDA-approved LIAISON® Rubella IgG Assay is used for the qualitative detection of IgG antibodies against the Rubella virus in human serum. Results are reported in IU/mL for informational reference only and are not intended for quantitative interpretation.
The cutoff value (Index = 1) is set at 10 IU/mL, based on calibration traceability to the WHO 1st International Standard for anti-Rubella Immunoglobulin, Human (1997). This follows CLSI guideline I/LA6-A, which recommends 10 IU/mL as the indicator of immune status.
Note: The stated linearity of the assay corresponds to an index value between 0 and 33, equivalent to 0–330 IU/mL. For values greater than 330 IU/mL, the assay is no longer linear, and results are reported as >330 IU/mL. The assay’s linearity has not been verified by the UW Virology Lab.
Synonyms
MMR Titer-Rubella, Rubella IgG
Components
| Code | Name |
|---|---|
| SDES32 | Rubella Immune Status Specimen |
| RUAS | Rubella Immune Status Result |
| RIUAB | Rubella Antibody Level |
| IN1 | Rubella Immune Status Interp |
Interpretation
Method
The FDA-approved LIAISON® Rubella IgG Assay is used for the qualitative detection of IgG antibodies against the Rubella virus in human serum is an indirect chemiluminescence immunoassay (CLIA).
Reference Range
See individual components
Ordering & Collection
Specimen Type
Collection
Blood: 5 mL blood in GOLD TOP serum separator tube (SST).
Also acceptable: 5 mL blood in ORANGE TOP rapid serum tube (RST) or RED TOP tube.
Quantity
requested: 1 mL serum
minimum: 0.3 mL serum
Processing
Blood: Harvest serum from whole blood within 24 hours of collection. Serum may be stored at 2-8°C (ice pack) for up to 7 days. Freeze at -20°C or colder for long term storage. Do not freeze/thaw.
Outside Laboratories: Store samples at 2–8°C and ship with an ice pack. Shipment time must not exceed 7 days from the collection date. Samples stored at 2–8°C for more than 7 days will be rejected.
If the time from collection to receipt at the University of Washington will exceed 7 days, ship samples on dry ice. Do not freeze/thaw samples.
Unacceptable samples: Cord blood, neonatal specimens, cadaver specimens, heat-inactivated specimens, or body fluids such as saliva, urine, amniotic fluid, pleural fluid or plasma. Specimens with obvious microbial contamination, lipemic or are grossly hemolyzed.
Performance
LIS Dept Code
Clinical Virology (CVIR)
Performing Location(s)
| Other |
Virology
206-685-8037 Virology Laboratory, Ste 320 |
|---|
Frequency
Monday-Friday
Available STAT?
No