Clinical and Research Background
Dr. Risques’ research focuses on the study of somatic mutations in aging and cancer with the ultimate goal of understanding how somatic evolution determines cancer risk and using this knowledge to develop better biomarkers for early cancer detection and prediction.
In addition to somatic mutations, the Risques lab is also interested in other genetic alterations that contribute to aging and cancer including telomere shortening and mitochondrial dysfunction. Current projects at the Risques lab involve the application of ultra-accurate deep sequencing to characterize age-related somatic mutations and their association with cancer risk; to detect cancer mutations in liquid biopsies, and to trace somatic evolution based on polyguanine tract mutations.
Research Interests
Cancer and Aging, Somatic Mutations, Early Cancer Detection, Deep Sequencing, Cancer Biomarkers
Academic and Medical Appointments
Associate Professor, University of Washington, Seattle, WA, 2019 - Present
Assistant Professor, University of Washington, Seattle, WA, 2013 - 2019
Acting Assistant Professor, University of Washington, Seattle, WA, 2011 - 2013
Acting Instructor, University of Washington, Seattle, WA, 2007 - 2011
Education and Training
Post-doctoral Fellow. Department of Pathology, University of Washington, Seattle, WA, USA, 2003 - 2007
Post-doctoral Associate. Department of Molecular Biology, Sidney Kimmel Cancer Center, San Diego, CA, USA, 2001 - 2003
PhD in Molecular and Cell Biology. Cancer Research Institute and Autonomous University of Barcelona, Spain, 1996 - 2001
BS in Biology. Autonomous University of Barcelona, Spain, 1992 - 1996
Publications
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Latest publications from PubMed