Porphobilinogen, Random Urine
General Information
Lab Name
Porphobilinogen, Random Urine
Lab Code
UPBGRG
Epic Name
Porphobilinogen, Random Urine
Description
STAT requests require approval from Lab Med Resident. Increased urinary porphobilinogen concentration in the presence of acute clinical symptoms is consistent with a biochemical diagnosis of acute porphyria, variegate porphyria, or hereditary coproporphyria. Normal concentrations may be seen in porphyria patients who are asymptomatic at the time of collection.
Synonyms
porphyria, spot urine
Components
| Code | Name |
|---|---|
| UPBGR | Porphobilinogen, Urine |
| UPBGRM | Porphobilinogen Method |
Interpretation
Method
Modified Mauzerall-Granick method
Reference Range
See individual components
Ref. Range Notes
The literature reference for this reference range is: Deacon AC, Elder GH. Front line tests for the investigation of suspected porphyria. J Clin Pathol 2001; 54:500-507.
Ordering & Collection
Specimen Type
Collection
RANDOM URINE: STAT specimens do not need preservative if delivered immediately to the laboratory.
RANDOM URINE: To ROUTINE specimens add approximately 5 g sodium bicarbonate for 30 mL or more urine (1 well rounded tsp). For urine samples less than 30 mL, add sodium bicarbonate to the minimum ratio of 2 mg per mL of urine. HMC Chemistry will provide aliquot tubes containing 200 mg sodium bicarbinate for about 10 mL of urine.
Mix well. Refrigerate in a dark bottle.
For 24-hour urine, see Porphobilinogen Quantitative, 24-h urine [UPBG]
Quantity
requested: 50 mL urine
minimum: 10 mL urine
Processing
Mix well. Refrigerate in a dark bottle.
Performance
LIS Dept Code
Chemistry, Harborview (CHH)
Performing Location(s)
Frequency
Monday to Friday, samples received in Special Chemistry by 11AM. Weekends and holidays, approved STAT only.
Available STAT?
with approval