A Genetic Disease that Mimics Premature Aging
Useful Information About Werner Syndrome and the WRN Gene:
Werner Syndrome International Registry
This site contains diagnostic criteria for WRN and contact information for a central repository of WS data and research and materials.
Werner Syndrome (WS) is an uncommon, autosomal recessive human genetic disease that mimics premature aging. Patients with WS appear to age rapidly following puberty, and are at increased risk of developing cancer and cardiovascular disease. Symptoms of WS include premature graying and loss of hair, bilateral cataracts, osteoporosis, atherosclerosis, diabetes and scleroderma-like changes and ulceration of the skin.
The WS associated gene has been identified and named WRN.
This website was primarily designed as a resource for clinicians and basic scientists interested in WS medicine and biology.
The information contained in this website is provided as a courtesy by the Department of Laboratory Medicine and Pathology at the University of Washington-Seattle (DLMP). The views and opinions of the website authors do not necessarily state or reflect those of the DLMP.
This information is designed for educational purposes only and is not provided as a professional service or as medical advice for specific patients. It is NOT a substitute for professional medical care and if you have, or suspect you may have, a health problem, you should consult your health care provider.
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